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Invitrogen™ Calpain 1 Polyclonal Antibody
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Catalog No. PIPA588234
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100 μL
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PIPA588234 100 μL
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Catalog No. PIPA588234 Supplier Invitrogen™ Supplier No. PA588234
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PDALKSRTIR KWNTTLYEGT WRRGSTAGGC RNYPATFWVN PQFKIRLDET DDPDDYGDRE SGCSFVLALM QKHRRRERRF GRDMETIGFA VYEVPPELVG QPAVHLKRDF FLANASRARS EQFINLREVS TRFRLPPGEY VVVPSTFEPN KEGDFVLRFF SEKSAGTVEL DDQIQA Positive Samples: A-549, BT-474, MCF7, Jurkat, PC-3; Cellular Location: Cell membrane, Cytoplasm.

The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calpain 1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.39 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene CAPN1
Gene Accession No. O35350, P07384, P97571
Gene Alias calcium activated neutral protease; calcium-activated neutral protease 1; calcium-activated neutral proteinase 1; calcium-dependent protease; calpain; calpain 1; calpain 1 large subunit; calpain 1, (mu/I) large subunit; calpain 1, large subunit; calpain mu-type; calpain, large polypeptide L1; calpain-1 catalytic subunit; Calpain-1 large subunit; Calpain-I; Calpain-II; CANP; CANP 1; Canp1; CANPL1; Capa1; Capa-1; Capn1; Cell proliferation-inducing gene 30 protein; cell proliferation-inducing protein 30; Cls1; I79_024883; micromolar calcium-activated neutral protease 1; micromolar calcium-activated neutral protease 1 isoform A; micromolar calcium-activated neutral protease 1 isoform B; micromolar calcium-dependent neutral protease large subunit; micromolar-calpain; mucalpain; mu-calpain; mu-calpin; muCANP; muCL; PIG30; SPG76
Gene Symbols CAPN1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 355-530 of human Calpain 1 (NP_0051772).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12333, 29153, 823
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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