Invitrogen™ Calpain 10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106623

Catalog No. PIPA5106623

Description

Antibody detects endogenous levels of total CAPN10.

The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.

Specifications

• Antigen: Calpain 10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAPN10
• Gene Alias: calcium-activated neutral proteinase 10; calpain 10; calpain-10; calpain-like protease CAPN10; CANP 10; CANP10; CAPN10; KIAA1845; NIDDM1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11132, 23830
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9ESK3, Q9HC96
• Gene Symbols: CAPN10
• Immunogen: A synthesized peptide derived from human CAPN10(Accession Q9HC96), corresponding to amino acid residues L34-K84.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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