Invitrogen™ Calpain 11 Monoclonal Antibody (2G2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA521265

Catalog No. PIMA521265

Description

Peptide Sequence: LLNRMAIKFK SFKTKGFGLD ACRCMINLMD KDGSGKLGLL EFKILWKKLK KWMDIFRECD QDHSGTLNSY EMRLVIEKAG IKLNNKVMQV LVARY.

The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.

Specifications

• Antigen: Calpain 11
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9UMQ6
• Gene Symbols: CAPN11
• Immunogen: CAPN11 (NP_008989, 557 a.a. ~ 651 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA
• Clone: 2G2
• Conjugate: Unconjugated
• Gene: CAPN11
• Gene Alias: calcium-activated neutral proteinase 11; calcium-activated neutral proteinase 11 {ECO:0000250; calcium-dependent thiol protease; calpain 11; calpain 11 {ECO:0000312; calpain11; Calpain-11; calpain-11; LOW QUALITY PROTEIN: calpain-11; CANP 11; CANP 11 {ECO:0000250; Capn11; capn11 {ECO:0000312; EMBL:AAH97256.1}; HIP2; LIG; RGD:1302946}; UniProtKB:Q9UMQ6}
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11131
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid