Invitrogen™ Calpain 13 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531179

Catalog No. PIPA531179

Description

Recommended positive controls: A549, HeLa. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.

Specifications

• Antigen: Calpain 13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAPN13
• Gene Alias: Calcium-activated neutral proteinase 13; calpain 13; calpain-13; CANP 13; CAPN13
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 92291
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.67 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q6MZZ7
• Gene Symbols: CAPN13
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Calpain 13. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG