Invitrogen™ Calpain 15 Monoclonal Antibody (4E2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524564

Catalog No. PIMA524564

Description

Peptide Sequence: HPKAYLHVQC DCTDSFNVVS TRGSLRTQDS VPPLHRQVLV ILSQLEGNAG FSITHRLAHR KAAQAFLSDW TASKGTHSPP LTPEVAGLHG PRPL.

The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.

Specifications

• Antigen: Calpain 15
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CAPN15
• Gene Alias: calpain 15; calpain-15; CAPN15; LOW QUALITY PROTEIN: calpain-15; small optic lobes homolog; Solh; zmp:0000001110
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 6650
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunocytochemistry
• Clone: 4E2
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: O75808
• Gene Symbols: CAPN15
• Immunogen: SOLH (NP_005623, 993 a.a. ~ 1086 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ