Invitrogen™ Calpain 15 Monoclonal Antibody (4E2)

Catalog No.	Quantity
PIMA524564	100 μg

Catalog No. PIMA524564 Supplier Invitrogen™ Supplier No. MA524564

Description

Mouse Monoclonal Antibody

Peptide Sequence: HPKAYLHVQC DCTDSFNVVS TRGSLRTQDS VPPLHRQVLV ILSQLEGNAG FSITHRLAHR KAAQAFLSDW TASKGTHSPP LTPEVAGLHG PRPL.

The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.

Specifications

• Antigen: Calpain 15
• Applications: ELISA, Immunocytochemistry
• Classification: Monoclonal
• Clone: 4E2
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene: CAPN15
• Gene Accession No.: O75808
• Gene Alias: calpain 15; calpain-15; CAPN15; LOW QUALITY PROTEIN: calpain-15; small optic lobes homolog; Solh; zmp:0000001110
• Gene Symbols: CAPN15
• Host Species: Mouse
• Immunogen: SOLH (NP_005623, 993 a.a. ~ 1086 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6650
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a κ