Invitrogen™ Calpain 15 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552888

Catalog No. PIPA552888

Description

Immunogen sequence: FLPVLNGVLP KPPAILGEPK GSCQEEAGPV RTAGLVATEP ARGQCEDKDE EEKEEQEEEE GAAEPRGGWA CPRCTLHNTP VASSCSVCGG PRRLSLPRIP PEALVVPE Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 76%.

The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.

Specifications

• Antigen: Calpain 15
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAPN15
• Gene Alias: calpain 15; calpain-15; CAPN15; LOW QUALITY PROTEIN: calpain-15; small optic lobes homolog; Solh; zmp:0000001110
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6650
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75808
• Gene Symbols: CAPN15
• Immunogen: Recombinant protein corresponding to Human Calpain 15. Recombinant protein control fragment (Product #RP-89312).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG