Invitrogen™ Calpain 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595965

Catalog No. PIPA595965

Description

Immunogen sequence: SDTYKKWKLT KMDGNWRRGS TAGGCRNYPN TFWMNPQYLI KLEEEDEDEE DGESGCTFLV GLIQKHRRRQ RKMGEDMHTI GFGIYEVPEE LSGQTNIHLS KNFFLTNRAR ERSDTFINLR EVLNRFKLPP GEYILVPSTF EPNKDGDFCI RVFSEKKADY QAVDDEIEAN LEEFDISEDD IDDGFRRLFA QLAGEDAEIS AFELQTILRR VLAKRQDIKS DGFSIETCKI MVDMLDSDGS GKLGLKEFYI LWTKIQKYQK IYREIDVDRS GTMNSYEMRK ALEEAGFKMP CQLHQVIVAR FADDQLIIDF DNFVRCLVRL ETLFKIFKQL D; Positive Samples: H460, A-549, HeLa, Mouse kidney, Mouse lung; Cellular Location: Cell membrane, Cytoplasm.

Mu-Calpain, also known as Calpain-I, and m-calpain, also known as Calpain-II, are intracellular, calcium-dependent cysteine proteases. Mu-calpain has a micromolar sensitivity (thus the mu-) as compared to the millimolar calcium sensitivity of m-calpain.

Specifications

• Antigen: Calpain 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAPN2
• Gene Alias: 80 kDa M-calpain subunit; AI326419; Calcium-activated neutral proteinase 2; calcium-dependent protease; CALP80; calpain 2; calpain 2, (m/II) large subunit; calpain 2, large [catalytic] subunit; calpain 2, large subunit; calpain II; calpain large polypeptide L2; Calpain M-type; calpain, large polypeptide L2; calpain-2 catalytic subunit; Calpain-2 large subunit; CANP 2; CANP2; CANPL2; CANPml; Capa2; Capa-2; CAPN2; cysteine proteinase; m-calpain; m-calpain 80 kDa large subunit; m-calpain large subunit; m-calpin; mCANP; millimolar-calpain
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12334, 29154, 824
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2.02 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O08529, P17655, Q07009
• Gene Symbols: CAPN2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-680 of human Calpain 2 (NP_0017392).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG