Invitrogen™ Calpain 9 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530405

Catalog No. PIPA530405

Description

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (89%), Rat (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Calpain 9
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAPN9
• Gene Alias: 2200003B16Rik; calpain 9; calpain-9; Capn9; Digestive tract-specific calpain; GC36; NCL4; nCL-4; New calpain 4; novel calpain large subunit-4; Protein CG36
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10753
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O14815
• Gene Symbols: CAPN9
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Calpain 9. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG