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Invitrogen™ Calpain 9 Polyclonal Antibody
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Catalog No. PIPA589435
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100 μL
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PIPA589435 100 μL
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Catalog No. PIPA589435 Supplier Invitrogen™ Supplier No. PA589435
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QEECSFLVAL MQKDRRKLKR FGANVLTIGY AIYECPDKDE HLNKDFFRYH ASRARSKTFI NLREVSDRFK LPPGEYILIP STFEPHQEAD FCLRIFSEKK AITRDMDGNV DIDLPEPPKP TPPDQETEEE QRFRALFEQV AGEDMEVTAE ELEYVLNAVL QKKKDIKFKK LSLISCKNII SLMDTSGNGK LEFDEFKVFW DKLKQWINLF LRFDADKSGT MSTYELRTAL KAAGFQLSSH LLQLIVLRYA DEELQLDFDD FLNCLVRLEN ASRVFQALST KNKEFIHLNI NEFIHLTMNI; Positive Samples: SGC-7901, HL60, HT-29, Mouse stomach, Mouse small intestine, Rat stomach, Rat small intestine.

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calpain 9
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene CAPN9
Gene Accession No. O14815, O35920, Q9D805
Gene Alias 2200003B16Rik; calpain 9; calpain-9; Capn9; Digestive tract-specific calpain; GC36; NCL4; nCL-4; New calpain 4; novel calpain large subunit-4; Protein CG36
Gene Symbols CAPN9
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 391-690 of human CAPN9 (NP_0066061).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10753, 116694, 73647
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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