Thermo Scientific Chemicals Calpain Inhibitor I, 95+%

Description

 

It inhibits apoptosis in thymocytes and metamyelocytes. It also inhibits cell cycle progression at the G1/S border and metaphase/anaphase in CHO cells by inhibiting cyclin B degradation. ALLN inhibits the proteolysis of IκBα and IκBβ by the ubiquitin-proteasome complex. ALLN also prevents nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 110044-82-1
• Molecular Formula: C20H37N3O4
• Molecular Weight (g/mol): 383.53
• InChI Key: FMYKJLXRRQTBOR-BZSNNMDCSA-N
• Synonym: Ac-LLnL-CHO; ALLN
• IUPAC Name: (2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-4-methyl-N-[(2S)-1-oxohexan-2-yl]pentanamide
• SMILES: CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)C=O

• Quantity: 5 mg
• Description: White
• Content And Storage: -30°C to -10°C
• For Use With (Application): An inhibitor of both Calpain I and II
• Formula Weight: 383.53
• Form: Powder
• Beilstein: 7656053
• Assay: 95+%

Safety and Handling

Recommended Storage

Store at -20°C

SDS

RUO – Research Use Only