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Invitrogen™ Calpain S1 Monoclonal Antibody (SP81)
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Catalog No. PIMA516326
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500 μL
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Catalog No. Quantity
PIMA516326 500 μL
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Catalog No. PIMA516326 Supplier Invitrogen™ Supplier No. MA516326
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Description

Rabbit Monoclonal Antibody

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is breast carcinoma.

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calpain S1
Applications Flow Cytometry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SP81
Conjugate Unconjugated
Formulation PBS with 1% BSA and <0.1% sodium azide; pH 7.6
Gene CAPNS1
Gene Accession No. O88456, P04632, Q64537
Gene Alias 30K; Calcium-activated neutral proteinase small subunit; calcium-dependent protease; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease, small subunit; calpain 4; calpain 4, small subunit (30K); calpain II regulatory subunit; calpain II regulatory subunit (EC 3.4.22.17); calpain regulatory subunit; Calpain small subunit 1; calpain, small polypeptide; calpain, small subunit 1; CALPAIN4; CANP; CANP small subunit; CANPS; Capa4; Capa-4; Capn4; CAPNS; CAPNS1; CDPS; CSS1; D7Ertd146e; small pol; unknown protein
Gene Symbols CAPNS1
Host Species Rabbit
Immunogen Synthetic peptide derived from internal region of human calpain protein.
Purification Method Protein A/G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12336, 29156, 826
Target Species Human, Mouse, Rat
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG
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