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Invitrogen™ Calponin 1 Monoclonal Antibody (1H5B5)
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Catalog No. PIMA538501
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100 μg
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Catalog No. Quantity
PIMA538501 100 μg
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Catalog No. PIMA538501 Supplier Invitrogen™ Supplier No. MA538501
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Description

Mouse Monoclonal Antibody

This antibody has been tested in indirect ELISA.

Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calponin 1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1H5B5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene CNN1
Gene Accession No. P51911
Gene Alias Basic calponin; calponin; calponin 1; calponin 1, basic, smooth muscle; calponin 1, smooth muscle; calponin H1, smooth muscle; Calponin-1; calponins, basic; CN; CNN1; CnnI; epididymis secretory protein Li 14; h1-calponin; HEL-S-14; similar to calponin 1, basic, smooth muscle; Sm-Calp; SMCC; smooth muscle calponin h1
Gene Symbols CNN1
Host Species Mouse
Immunogen Purified recombinant fragment of human CNN1 (aa: 16-165) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1264
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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