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Calponin 1 Monoclonal Antibody (EP798Y), Invitrogen™

Catalog No. PIMA514464
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PIMA514464 1 mL
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Catalog No. PIMA514464 Supplier Thermo Scientific Supplier No. MA514464
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Description

Rabbit Monoclonal Antibody

MA5-14464 targets Calponin-1 in IHC (P) applications and shows reactivity with Human samples. The MA5-14464 immunogen is a synthetic peptide derived from near the C-terminus of human Calponin-1.

Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calponin 1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone EP798Y
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation tissue culture supernatant with 0.09% sodium azide
Gene CNN1
Gene Accession No. P51911
Gene Alias Basic calponin; calponin; calponin 1; calponin 1, basic, smooth muscle; calponin 1, smooth muscle; calponin H1, smooth muscle; Calponin-1; calponins, basic; CN; CNN1; CnnI; epididymis secretory protein Li 14; h1-calponin; HEL-S-14; similar to calponin 1, basic, smooth muscle; Sm-Calp; SMCC; smooth muscle calponin h1
Gene Symbols CNN1
Host Species Rabbit
Immunogen A synthetic peptide derived from near the C-terminus of human Calponin-1
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1264
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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