Invitrogen™ Calreticulin Recombinant Rabbit Monoclonal Antibody (SAIC-16D-6B9)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA547895

Catalog No. PIMA547895

Description

Specificity: Recognises human CALR.

Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.

Specifications

• Antigen: Calreticulin
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P27797
• Gene Symbols: CALR
• Immunogen: Peptide GLQTSQDAR, derived from the calcium-binding protein chaperone Calreticulin, conjugated to KLH.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG κ

• Applications: ELISA, Flow Cytometry, Western Blot, Immunocytochemistry, Mass Spectrometry
• Clone: SAIC-16D-6B9
• Conjugate: Unconjugated
• Gene: CALR
• Gene Alias: Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 811
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid