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Calsequestrin 2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1C10A1, Proteintech
Mouse Monoclonal Antibody
$518.60
Specifications
| Antigen | Calsequestrin 2 |
|---|---|
| Clone | 1C10A1 |
| Concentration | 1 mg/mL |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-173-6846
|
Proteintech Group Inc
664191IG150UL |
150 μL |
Each of 1 for $518.60
|
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Description
Calsequestrin (CASQ) is a Ca2+-binding protein present primarily in junctional sarcoplasmic reticulum of skeletal and cardiac muscle; the cardiac form (CASQ2) is encoded by a separate gene. The primary role of CASQ2 is buffering of the sarcoplasmic reticulum Ca2+ ions, but another role for CASQ2 has emerged recently: CASQ2 regulates the open probability of ryanodine receptor 2 (RyR2). Mutations in CASQ2 cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.Specifications
| Calsequestrin 2 | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Calsequestrin 2, CASQ2, PDIB2 | |
| Casq2 | |
| IgG2a | |
| Protein A | |
| Antibody |
| 1C10A1 | |
| Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| Mouse | |
| Human, Mouse, Pig, Rat | |
| O09161, O14958, O18934, P51868 | |
| 12373, 29209, 397436, 845 | |
| Calsequestrin 2 Fusion Protein Ag13246 | |
| Primary | |
| -20°C | |
| CASQ2 |
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