Calsequestrin Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-5046	100 μL

Catalog No. 50-198-5046 Supplier Bioss Supplier No. BS2961R

Description

Rabbit Polyclonal Antibody

The sarcoplasmic reticulum (SR) is, in part, responsible for maintaining the level of intracellular calcium in cardiac and skeletal muscle by storing and releasing calcium. Several intralumenal SR calcium binding proteins have been identified, the most prominent of these is calsequestrin. Calsequstrin is a calcium binding protein known to sequester calcium accumulated in the sarcoplasmic reticulum of muscle cells during relaxation and is found discretely localized to the junctional and corbular (terminal cisternae) SR. Calsequestrin functions to localize calcium near the junctional face of the terminal cisternae from which calcium can be released into the cytosol via the ryanodine receptor. This protein is highly acidic and has a large capacity and moderate to low affinity for calcium.

Specifications

• Antigen: Calsequestrin
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: CASQ1
• Gene Accession No.: P31415
• Gene Alias: Aspartactin; calmitin; Calmitine; calsequestrin 1; calsequestrin 1 (fast-twitch, skeletal muscle); Calsequestrin, skeletal muscle isoform; Calsequestrin-1; calsquestrin 1; CASQ; CASQ1; CSQ; CSQ1; CSQ-1; Laminin-binding protein; PDIB1; sCSQ; skeletal muscle calsequestrin 1; VMCQA
• Gene Symbols: CASQ1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Calsequestrin.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 844
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG