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Invitrogen™ Calumenin Monoclonal Antibody (6B4)
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Catalog No. PIMA518318
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100 μL
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Catalog No. Quantity
PIMA518318 100 μL
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Catalog No. PIMA518318 Supplier Invitrogen™ Supplier No. MA518318
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Description

Mouse Monoclonal Antibody

This antibody detects endogenous protein at a molecular weight of 45 kDa, although the predicted MW is 37 kDa. Purity is >95% by SDS-PAGE.

Caluminin is a 315 amino acid Ca2+-binding member of the CREC, EF-hand protein family. Calumenin is a secreted protein t hat contains six Ca2+-binding (EF-hand) motifs and is expressed in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus. In the presence of Ca2+, Calumenin interacts with serum amyloid P component (SAP) and, together, they may play a role in the immunological defense system and participate in amyloidosis, the pathological formation of amyloid deposits in different types of tissues. Calumenin has an inhibitory effect on the vitamin K-dependent g-carboxylation system which converts vitamin K-dependent proteins to Gla-containing proteins. Calumenin may also be involved in the pathophysiology of thrombosis and/or wound healing by acting in an autocrine or paracrine manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calumenin
Applications Western Blot
Classification Monoclonal
Clone 6B4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Calu
Gene Accession No. O35887, O43852
Gene Alias 9530075H20Rik; CALU; Calumenin; Cbp50; CBP-50; Crocalbin; crocalbin-like protein; IEF SSP 9302; multiple EF-hand protein; Rcn; reticulocalbin
Gene Symbols Calu
Host Species Mouse
Immunogen Synthetic peptide corresponding to amino acids C-terminus of human Calumenin.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12321, 813
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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