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Invitrogen™ Calumenin Polyclonal Antibody
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Catalog No. PIPA5100420
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100 μL
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PIPA5100420 100 μL
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Catalog No. PIPA5100420 Supplier Invitrogen™ Supplier No. PA5100420
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Calumenin.

Caluminin is a 315 amino acid Ca2+-binding member of the CREC, EF-hand protein family. Calumenin is a secreted protein t hat contains six Ca2+-binding (EF-hand) motifs and is expressed in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus. In the presence of Ca2+, Calumenin interacts with serum amyloid P component (SAP) and, together, they may play a role in the immunological defense system and participate in amyloidosis, the pathological formation of amyloid deposits in different types of tissues. Calumenin has an inhibitory effect on the vitamin K-dependent g-carboxylation system which converts vitamin K-dependent proteins to Gla-containing proteins. Calumenin may also be involved in the pathophysiology of thrombosis and/or wound healing by acting in an autocrine or paracrine manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calumenin
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Calu
Gene Accession No. O35887, O43852
Gene Alias 9530075H20Rik; CALU; Calumenin; Cbp50; CBP-50; Crocalbin; crocalbin-like protein; IEF SSP 9302; multiple EF-hand protein; Rcn; reticulocalbin
Gene Symbols Calu
Host Species Rabbit
Immunogen A synthesized peptide derived from human CALU(Accession O43852), corresponding to amino acid residues L118-D168.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12321, 813
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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