CAMK2B Mouse anti-Human, Clone: OTI8D9, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF808345

Catalog No. 50-166-8792

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.

Specifications

• Antigen: CAMK2B
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CAMK2B
• Gene Alias: CAM2, CAMK2, CAMKB, MRD54
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 816
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI8D9
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q13554
• Gene Symbols: CAMK2B
• Immunogen: Human recombit protein fragment corresponding to amino acids 311-385 of human CAMK2B produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1