Invitrogen™ CAMK2N1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA523740

Catalog No. PIPA523740

Description

This antibody is predicted to react with bovine and rat based on sequence homology.

Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity). Plays a role in the maintenance of long-term retrieval- induced memory in response to contextual fear (By similarity). Modulates blood pressure and vascular reactivity via regulation of CAMK2 activity in addition to regulation of left ventricular mass (By similarity). Mediates the NLRP3 inflammasome in cardiomyocytes via acting as an inhibitor of the MAPK14/p38 and MAPK8/JNK pathways, thereby regulating ventricular remodeling and cardiac rhythm post- myocardial infarction (By similarity). Negatively effects insulin sensitivity and promotes lipid formation in adipose tissues independent of CAMK2 signaling (By similarity).

Specifications

• Antigen: CAMK2N1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAMK2N1
• Gene Alias: 1810006K23Rik; AI848599; AI891706; calcium/calmodulin dependent protein kinase II inhibitor 1; calcium/calmodulin-dependent protein kinase II inhibitor 1; calcium/calmodulin-dependent protein kinase II inhibitor alpha; Camk2n1; CaMKII inhibitor protein alpha; caMKII inhibitory protein alpha; CaMKIINalpha; CaMKIIN-alpha; mCaMKIINalpha; PRO1489; RP11-401M16.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 55450, 66259
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q6QWF9, Q7Z7J9
• Gene Symbols: CAMK2N1
• Immunogen: KLH conjugated synthetic peptide between 37-65 amino acids from the C-terminal region of human CAMK2N1.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG