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Invitrogen™ CaMKII beta Polyclonal Antibody
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Catalog No. PIPA582911
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100 μL
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PIPA582911 100 μL
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Catalog No. PIPA582911 Supplier Invitrogen™ Supplier No. PA582911
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TRNFSVGRQT TAPATMSTAA SGTTMGLVEQ AKSLLNKKAD GVKPQTNSTK NSAAATSPKG TLPPAALEPQ TTVIH Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 96%.

CAMK2B (CaMKII beta) is a serine/threonine kinase that plays a role in synaptic plasticity, synaptic vesicle mobilization and regulation of gene expression. As a dominant kinase in the central nervous system it may function in long term potentiation and neurotransmitter release. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CaMKII beta
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CAMK2B
Gene Accession No. P28652, Q13554
Gene Alias Ca++/calmodulin-dependent protein kinase II beta subunit; calcium/calmodulin dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II subunit beta; CaM kinase II beta subunit; caM kinase II subunit beta; CAM2; CaMK II; CAMK2; CAMK2B; Camk2d; CAMKB; caMK-II subunit beta; caM-kinase II beta chain; Ck2b; hypothetical protein LOC525416; MGC29528; proline rich calmodulin-dependent protein kinase; β CaMKII; βCaMKII
Gene Symbols CAMK2B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CAMK2B.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12323, 816
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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