Invitrogen™ CaMKII Pan Recombinant Rabbit Monoclonal Antibody (SU03-57)

Catalog No.	Quantity
PIMA532125	100 μL

Catalog No. PIMA532125 Supplier Invitrogen™ Supplier No. MA532125

Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+/calmodulin (CaM) binding and autophosphorylation and has been implicated in regulation of the cell cycle and transcription. It is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.

Specifications

• Antigen: CaMKII Pan
• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: SU03-57
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene: Camk2b
• Gene Accession No.: P08413, P11275, P11730, P11798, P15791, P28652, Q13554, Q13555, Q13557, Q6PHZ2, Q923T9, Q9UQM7
• Gene Alias: [d]-CaMKII; 2810011D23Rik; 8030469K03Rik; alpha CaM kinase II; alpha-CaMKII; Ca++/calmodulin-dependent protein kinase 2 delta subunit; Ca++/calmodulin-dependent protein kinase II beta subunit; Ca++/calmodulin-dependent protein kinase II delta subunit; Ca++/calmodulin-dependent protein kinase II, delta subunit; Ca2+/calmodulin-dependent protein kinase II; Ca2+/calmodulin-dependent protein kinase II alpha; calcium/calmodulin dependent protein kinase II alpha; calcium/calmodulin dependent protein kinase II beta; calcium/calmodulin dependent protein kinase II delta; calcium/calmodulin dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; calcium/calmodulin-dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase II alpha subunit; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase II, delta; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II delta chain; calcium/calmodulin-dependent protein kinase type II gamma chain; calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type II subunit beta; calcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase type II subunit gamma; CaM kinase II alpha subunit; CaM kinase II beta subunit; CaM kinase II delta subunit; caM kinase II subunit alpha; CaM kinase II subunit beta; caM kinase II subunit delta; CaM kinase II subunit gamma; CAM2; CAMK; CaMK II; CAMK1; Camk2; Camk2a; Camk2b; Camk2d; Camk2g; CAMKA; CAMKB; CAMKD; CAMKG; Camki; CaMKII; CAMK-II; CaMK-II alpha subunit; CaMK-II delta subunit; caMK-II subunit alpha; caMK-II subunit beta; caMK-II subunit delta; caMK-II subunit gamma; CaMKIINalpha; CaM-kinase II alpha chain; CaM-kinase II beta chain; CaM-kinase II delta chain; caM-kinase II gamma chain; Ck2b; KIAA0968; Kiaa4163; mKIAA0968; PK2CDD; PKCCD; proline rich calmodulin-dependent protein kinase; R74975; RATCAMKI
• Gene Symbols: Camk2a, Camk2b, CAMK2D, Camk2g
• Host Species: Rabbit
• Immunogen: Synthetic peptide within Human CaMKII aa 201-250.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 108058, 12322, 12323, 12325, 171140, 24245, 24246, 25400, 815, 816, 817, 818
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG