Invitrogen™ CaMKK alpha Monoclonal Antibody (4A11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA522743

Catalog No. PIMA522743

Description

Peptide Sequence: EGGPAVCCQD PRAELVERVA AIDVTHLEEA DGGPEPTRNG VDPPPRARAA SVIPGSTSRL LPARPSLSAR KLSLQERPAG SYLEAQAGPY ATGPASHIS.

CAMKK1 (CAMKKA) is a serine/threonine protein kinase family member, and belongs to the Ca2+/calmodulin-dependent protein kinase subfamily. The product of CaMKK alpha is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. CAMKK1 functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for CaMKK alpha. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Specifications

• Antigen: CaMKK alpha
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q8N5S9
• Gene Symbols: CAMKK1
• Immunogen: CAMKK1 (AAH31647.1, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 4A11
• Conjugate: Unconjugated
• Gene: CAMKK1
• Gene Alias: AI846603; alpha CaMKK; calcium calmodulin dependent protein kinase kinase alpha; calcium/calmodulin dependent protein kinase kinase 1; calcium/calmodulin-dependent protein kinase kinase 1; calcium/calmodulin-dependent protein kinase kinase 1, alpha; calcium/calmodulin-dependent protein kinase kinase alpha; CaM-kinase IV kinase; caM-kinase kinase 1; caM-kinase kinase alpha; Camkk; caMKK 1; caM-KK 1; caMKK alpha; CaM-KK alpha; CAMKK alpha protein; CAMKK1; CAMKKA; CaMKKalpha
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84254
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid