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Invitrogen™ CaMKK alpha Polyclonal Antibody
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Catalog No. PIPA547635
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100 μg
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Catalog No. Quantity
PIPA547635 100 μg
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Catalog No. PIPA547635 Supplier Invitrogen™ Supplier No. PA547635
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Description

Sheep Polyclonal Antibody

This antibody detects endogenous human and rat CaMKK alpha in Western blots. In Western blots, this antibody does not cross-react with recombinant human CaMKK beta. Reconstitute at 0.2 mg/mL in sterile PBS.

CAMKK1 (CAMKKA) is a serine/threonine protein kinase family member, and belongs to the Ca2+/calmodulin-dependent protein kinase subfamily. The product of CaMKK alpha is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. CAMKK1 functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for CaMKK alpha. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CaMKK alpha
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene CAMKK1
Gene Accession No. P97756, Q8N5S9
Gene Alias AI846603; alpha CaMKK; calcium calmodulin dependent protein kinase kinase alpha; calcium/calmodulin dependent protein kinase kinase 1; calcium/calmodulin-dependent protein kinase kinase 1; calcium/calmodulin-dependent protein kinase kinase 1, alpha; calcium/calmodulin-dependent protein kinase kinase alpha; CaM-kinase IV kinase; caM-kinase kinase 1; caM-kinase kinase alpha; Camkk; caMKK 1; caM-KK 1; caMKK alpha; CaM-KK alpha; CAMKK alpha protein; CAMKK1; CAMKKA; CaMKKalpha
Gene Symbols CAMKK1
Host Species Sheep
Immunogen E. coli-derived recombinant human CaMKK alpha Met1-Ser132.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 60341, 84254
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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