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Invitrogen™ CaMKK alpha Polyclonal Antibody
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Catalog No. PIPA578908
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100 μg
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Catalog No. Quantity
PIPA578908 100 μg
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Catalog No. PIPA578908 Supplier Invitrogen™ Supplier No. PA578908
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Brain Tissue, Rat Brain Tissue, Mouse Brain Tissue, Mouse Brain Tissue, rat brain tissue, mouse brain tissue, human U-87MG whole cell. IHC: Rat Brain Tissue.

CAMKK1 (CAMKKA) is a serine/threonine protein kinase family member, and belongs to the Ca2+/calmodulin-dependent protein kinase subfamily. The product of CaMKK alpha is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. CAMKK1 functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for CaMKK alpha. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CaMKK alpha
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene CAMKK1
Gene Accession No. P97756, Q8N5S9, Q8VBY2
Gene Alias AI846603; alpha CaMKK; calcium calmodulin dependent protein kinase kinase alpha; calcium/calmodulin dependent protein kinase kinase 1; calcium/calmodulin-dependent protein kinase kinase 1; calcium/calmodulin-dependent protein kinase kinase 1, alpha; calcium/calmodulin-dependent protein kinase kinase alpha; CaM-kinase IV kinase; caM-kinase kinase 1; caM-kinase kinase alpha; Camkk; caMKK 1; caM-KK 1; caMKK alpha; CaM-KK alpha; CAMKK alpha protein; CAMKK1; CAMKKA; CaMKKalpha
Gene Symbols CAMKK1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of mouse CaMKK (10-31aa QDPRAELVDRVAAINVAHLEEA).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55984, 60341, 84254
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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