CAMLG Monoclonal Antibody (OTI1A3), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-5047	100 μL
50-254-0385	30 μL

Catalog No. 50-167-5047 Supplier OriGene Supplier No. TA504329

Description

Mouse Monoclonal Antibody

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Specifications

• Antigen: CAMLG
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI1A3
• Concentration: 0.58 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: CAMLG
• Gene Accession No.: P49069
• Gene Alias: CAML, GET2
• Gene Symbols: CAMLG
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human CAMLG produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 819
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1