Invitrogen™ CAMLG Monoclonal Antibody (OTI2H3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525893

Catalog No. PIMA525893

Description

CAMLG Monoclonal Antibody for Western Blot, ICC/IF, Flow

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Specifications

• Antigen: CAMLG
• Classification: Monoclonal
• Concentration: 0.63 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P49069
• Gene Symbols: CAMLG
• Immunogen: Full length human recombinant protein of CAMLG produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: OTI2H3
• Conjugate: Unconjugated
• Gene: CAMLG
• Gene Alias: AI385748; calcium modulating ligand; calcium signal-modulating cyclophilin ligand; calcium-modulating cyclophilin ligand; calcium-signal modulating cyclophilin ligand; CAML; Camlg; cyclophilin B-binding protein; GET2
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 819
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid