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Invitrogen™ CAMLG Polyclonal Antibody
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Catalog No. PIPA562655
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100 μL
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PIPA562655 100 μL
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Catalog No. PIPA562655 Supplier Invitrogen™ Supplier No. PA562655
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GDKLDSFIKP PECSSDVNLE LRQRNRGDLT ADSVQRGSRH GLEQYLSRFE EAMKLRKQLI SEKPSQEDGN TTEE Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 88%.

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CAMLG
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CAMLG
Gene Accession No. P49069
Gene Alias AI385748; calcium modulating ligand; calcium signal-modulating cyclophilin ligand; calcium-modulating cyclophilin ligand; calcium-signal modulating cyclophilin ligand; CAML; Camlg; cyclophilin B-binding protein; GET2
Gene Symbols CAMLG
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CAMLG. Recombinant protein control fragment (Product #RP-101677).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 819
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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