CAMLG Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-4049	Proteintech Group Inc 233271AP150UL	150 μL

Description

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Specifications

• Antigen: CAMLG
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P49069, P49070
• Gene ID (Entrez): 12328, 81715, 819
• Immunogen: CAMLG Fusion Protein Ag19915
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CAMLG

• Concentration: 0.3 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: calcium modulating ligand, CAML, CAMLG
• Gene Symbols: Camlg
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody