Invitrogen™ CAND1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA581288

Catalog No. PIPA581288

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human CAND1.

CAND1 enhances transcription from various types of promoters. It is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site. CAND1 disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins.

Specifications

• Antigen: CAND1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAND1
• Gene Alias: 2310038O07Rik; 6330512O03Rik; AI195005; AI846556; CAND1; cullin associated and neddylation disassociated 1; cullin associated and neddylation dissociated 1; cullin-associated and neddylation-dissociated 1; cullin-associated and neddylation-dissociated protein 1; Cullin-associated NEDD8-dissociated protein 1; D10Ertd516e; DKFZp434M1414; fb78a05; FLJ10114; FLJ10929; FLJ38691; FLJ90441; KIAA0829; mKIAA0829; p120 CAND1; TBP interacting protein; TBP-interacting protein; TBP-interacting protein 120A; TBP-interacting protein of 120 kDa A; TBP-interacting protein TIP120A; TIP120; TIP120 protein; TIP120A; Tp120a; wu:fb78a05; zgc:55729
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 55832
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q86VP6
• Gene Symbols: CAND1
• Immunogen: A synthetic peptide corresponding to the N-terminus of the Human CAND1/TIP120A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov