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Invitrogen™ CAND1 Polyclonal Antibody
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Catalog No. PIPA565972
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100 μL
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PIPA565972 100 μL
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Catalog No. PIPA565972 Supplier Invitrogen™ Supplier No. PA565972
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DALSCLYVILC NHSPQVFHPH VQALVPPVVA CVGDPFYKIT SEALLVTQQL VKVIRPLDQP SSFDATPYIK DLFTCT Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.

CAND1 enhances transcription from various types of promoters. It is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site. CAND1 disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CAND1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CAND1
Gene Accession No. Q86VP6
Gene Alias 2310038O07Rik; 6330512O03Rik; AI195005; AI846556; CAND1; cullin associated and neddylation disassociated 1; cullin associated and neddylation dissociated 1; cullin-associated and neddylation-dissociated 1; cullin-associated and neddylation-dissociated protein 1; Cullin-associated NEDD8-dissociated protein 1; D10Ertd516e; DKFZp434M1414; fb78a05; FLJ10114; FLJ10929; FLJ38691; FLJ90441; KIAA0829; mKIAA0829; p120 CAND1; TBP interacting protein; TBP-interacting protein; TBP-interacting protein 120A; TBP-interacting protein of 120 kDa A; TBP-interacting protein TIP120A; TIP120; TIP120 protein; TIP120A; Tp120a; wu:fb78a05; zgc:55729
Gene Symbols CAND1
Host Species Rabbit
Immunogen Recombinant Human CAND1. Recombinant protein control fragment (Product #RP-105025).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55832
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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