CAND1Rabbit anti-Human, Polyclonal, Rockland™

Catalog No.	Quantity
50-199-0096	100 μL

Catalog No. 50-199-0096 Supplier Rockland Immunochemicals Supplier No. 100401A11

Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This product reacts with human, rat and mouse CAND1/TIP120A. Cross reactivity does occur with human, rat and mouse CAND2/TIP120B. Cross reactivity with CAND1 from other sources is not known.

CAND1 enhances transcription from various types of promoters. It is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site. CAND1 disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins.

Specifications

• Antigen: CAND1
• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 85 mg/mL
• Conjugate: Unconjugated
• Formulation: Antibody with 0.01% sodium azide; pH
• Gene: CAND1
• Gene Accession No.: Q86VP6
• Gene Alias: 2310038O07Rik; 6330512O03Rik; AI195005; AI846556; BOS_5239; CAND1; cullin associated and neddylation disassociated 1; cullin associated and neddylation dissociated 1; cullin-associated and neddylation-dissociated 1; Cullin-associated and neddylation-dissociated protein 1; Cullin-associated NEDD8-dissociated protein 1; D10Ertd516e; DKFZp434M1414; fb78a05; FLJ10114; FLJ10929; FLJ38691; FLJ90441; Kiaa0829; mKIAA0829; p120 CAND1; TBP interacting protein; TBP-interacting protein; TBP-interacting protein 120A; TBP-interacting protein of 120 kDa A; TBP-interacting protein TIP120A; TIP120; TIP120 protein; TIP120A; Tp120a; wu:fb78a05; zgc:55729
• Gene Symbols: CAND1
• Host Species: Rabbit
• Immunogen: This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 11-24 of Human CAND1/TIP120A (N-terminal) coupled to KLH.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 55832
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid