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CAP Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989322
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100 μL
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50-198-9322 100 μL
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Catalog No. 50-198-9322 Supplier Bioss Supplier No. BS9759R
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Rabbit Polyclonal Antibody

BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.

Specifications

Antigen CAP
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene BRD4
Gene Accession No. O60885
Gene Alias BOS_7204; Brd4; BRD4-NUT FUSION; Brd5; bromodomain containing 4; bromodomain-containing 4; bromodomain-containing 5; Bromodomain-containing protein 4; CAP; chromosome-associated protein; fsh-like protein; HUNK1; HUNKI; Mcap; Mitotic chromosome-associated protein; Protein HUNK1; WI-11513
Gene Symbols BRD4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Brd4/CAP.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23476
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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