Invitrogen™ CAPG Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596638

Catalog No. PIPA596638

Description

Immunogen sequence: MYTAIPQSGS PFPGSVQDPG LHVWRVEKLK PVPVAQENQG VFFSGDSYLV LHNGPEEVSH LHLWIGQQSS RDEQGACAVL AVHLNTLLGE RPVQHREVQG NESDLFMSYF PRGLKYQEGG VESAFHKTST GAPAAIKKLY QVKGKKNIRA TERALNWDSF NTGDCFILDL GQNIFAWCGG KSNILERNKA RDLALAIRDS ERQGKAQVEI VTDGEEPAEM IQVLGPKPAL KEGNPEEDLT ADKANAQAAA LYKVSDATGQ MNLTKVADSS PFALELLISD DCFVLDNGLC GKIYIWKGRK ANEKERQAAL QVAEGFISRM QYAPNTQVEI LPQGHESPIF KQFFKDWK; Positive Samples: THP-1, HL-60, Mouse lung, Mouse spleen, Rat heart, Rat lung; Cellular Location: Cytoplasm, Melanosome, Nucleus.

This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described.

Specifications

• Antigen: CAPG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAPG
• Gene Alias: Actin regulatory protein CAP-G; actin-capping protein GCAP39; actin-regulatory protein CAP-G; AFCP; Capg; capping actin protein, gelsolin like; capping protein (actin filament), gelsolin-like; epididymis secretory protein Li 66; gCap39; gelsolin-like capping protein; HEL-S-66; macrophage capping protein; macrophage-capping protein; mbh1; MCP; myc basic motif homolog 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12332, 297339, 822
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.34 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P24452, P40121, Q6AYC4
• Gene Symbols: CAPG
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-348 of human CAPG (NP_0017382).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG