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Invitrogen™ CADPS2 Polyclonal Antibody
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Catalog No. PIPA520518
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100 μg
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Catalog No. Quantity
PIPA520518 100 μg
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Catalog No. PIPA520518 Supplier Invitrogen™ Supplier No. PA520518
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-20518 can be used with blocking peptide PEP-0638.

CAPS2 and the related protein CAPS1 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. Like CAPS1, numerous isoforms of CAPS2 are known to exist. These isoforms show distinct expression patterns in the brain. For example, CAPS2b showed high expression in the developing cerebellum. Furthermore, one version of CAPS2 mRNA that lacks exon 3 is detected in some autistic patients, suggesting that the differential expression pattern of CAPS2 is involved in neuronal development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CADPS2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CADPS2
Gene Accession No. Q86UW7, Q8BYR5
Gene Alias A230044C21Rik; Ca++-dependent secretion activator 2; Ca2+ dependent secretion activator 2; Ca2+-dependent activator protein for secretion 2; Cadps2; calcium dependent secretion activator 2; calcium-dependent activator protein for secretion 2; Calcium-dependent secretion activator 2; calcyphosin-2; calcyphosine 2; Calcyphosine-2; calcyphosphine 2; Caps2; CAPS-2; cerebellum postnatal development associated protein 2; Cpd2; KIAA1591; RGD1559440; UG0636c06
Gene Symbols CADPS2
Host Species Rabbit
Immunogen A 19 amino acid peptide near the center of the human CAPS2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 312166, 320405, 93664
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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