Cytiva Capto™ L Chromatography Medium

Description

Capto L is a BioProcess chromatography medium (resin) for the capture of antibodies and antibody fragments.

Capto L is suitable for the capture of a wide range of antibody fragments such as Fabs, single-chain variable fragments (scFv), and domain antibodies (Dabs).

• High binding capacity, low ligand leakage, and selectivity for a broad range of antibody fragments reduces process time and amount of medium.
• Enables a platform approach for purification of antibody fragments.
• Increased productivity, process economy, and process design flexibility due to rigid matrix.
• The high binding capacity and selectivity for a broad range of antibody fragments makes Capto L an excellent capture platform for antibody fragments containing kappa light chains.
• Using Capto L requires minimal optimization and it produces high purity in one separation step.
• Capto L provides several advantages in manufacturing processes because the high selectivity of affinity capture reduces the number of subsequent polishing steps.

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Specifications

• Product Type: Capto L chromato graphy media
• Quantity: 25 mL
• Height (English): 7.87 in.
• Height (Metric): 200mm
• Flow Rate: <500 cm/hr.
• Ligand Type: Recombinant Protein L (E. coli), mammalian free
• pH Range: 2 to 10
• Particle Size: 85μm
• Support Type: Highly Cross-linked Agarose
• Content And Storage: 2° to 8°C
• For Use With (Application): High binding capacity, low ligand leakage and selectivity for a broad range of Antibody fragments reduces process time and amount of medium
• Matrix: Capto L Chromatography media