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Carbenicillin Disodium Salt, MP Biomedicals™

Catalog No. MP21950922 Shop All MP Biomedicals, Inc Products
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MP21950922 250 mg
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Catalog No. MP21950922 Supplier MP Biomedicals, Inc Supplier No. 02195092.2
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Description

Displays antipseudomonal and antiproteal effects. Carbenicillin Disodium Salt, MP Biomedicals is a carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface

Carbenicillin is a semi-synthetic antibiotic that is an analog to ampicillin. It is derived from benzyl penicillin by substituting the a-carboxyl group in the benzyl side chain. It is completely ionized in the blood and is about 50% reversibly protein bound in plasma. Its tissue distribution is similar to other penicillins.

Susceptible bacteria include gram-positive and gram-negative bacteria abd pseudomonas.Though it has substantial in vitro activity against a variety of both gram-positive and gram-negative microorganisms, the most important aspect of its profile is in its antipseudomonal and antiproteal effect.

Carbenicillin Disodium Salt is used for selection of ampr transformed cells and to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 4800-94-6
Molecular Formula C17H16N2Na2O6S
Molecular Weight (g/mol) 422.36
MDL Number MFCD00077683
InChI Key RTYJTGSCYUUYAL-YCAHSCEMSA-L
Synonym α-Carboxybenzylpenicillin
PubChem CID 20933
ChEBI CHEBI:34609
IUPAC Name disodium;(2S,5R,6R)-6-[(2-carboxylato-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
SMILES [Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)C3=CC=CC=C3)C(=O)N2[C@H]1C([O-])=O

Specifications

Physical Form Powder
Potency >650μg/mg
Concentration Working Concentration: 105u/L (5-50μg/mL) in cell culture; approximately 200mg/kg in vivo.
Quantity 250 mg
Solubility Information Soluble in water (50mg/mL) and alcohol
Formula Weight 422.4

Safety and Handling

Recommended Storage Store at 4°C, desiccate.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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