Invitrogen™ Carbonic Anhydrase I Recombinant Rabbit Monoclonal Antibody (0G10F8)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535508

Catalog No. PIMA535508

Description

Immunogen sequence: KVLDALQAIK TKGKRAPFTN FDPSTLLPSS LDFWTYPGSL THPPLYESVT WIICKESISV SSEQLAQFRS LLSNVEGDNA VPMQHNNRPT QPLKGRTVRA SF.

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.

Specifications

• Antigen: Carbonic Anhydrase I
• Classification: Recombinant Monoclonal
• Concentration: 0.75 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: B0BNN3, P13634
• Gene Symbols: Car1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-261 of human Carbonic Anhydrase 1 (CA1) (NP_0017291).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 0G10F8
• Conjugate: Unconjugated
• Gene: Car1
• Gene Alias: AW555628; CA I; CA1; ca1 {ECO:0000250; CAB; CA-I; CA-I {ECO:0000250; Car1; Car-1; Carbonate dehydratase I; carbonate dehydratase I {ECO:0000250; carbonic anhydrase 1; carbonic anhydrase 1 {ECO:0000250; Carbonic anhydrase B; carbonic anhydrase I; carbonic anhydrase I {ECO:0000250; epididymis secretory protein Li 11; HEL-S-11; UniProtKB:P00915}
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12346, 310218
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid