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Invitrogen™ Carbonic Anhydrase IX Recombinant Rabbit Monoclonal Antibody (053), FITC
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Catalog No. PIMA540980
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100 Tests
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Catalog No. Quantity
PIMA540980 100 Tests
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Catalog No. PIMA540980 Supplier Invitrogen™ Supplier No. MA540980
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Description

Rabbit Recombinant Monoclonal Antibody

May be stored for twelve months without detectable loss of activity. Protect from prolonged exposure to light and do not freeze. Sodium azide is toxic to cells and should be disposed of properly so flush with large volumes of water during disposal.

Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CA IX is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increased cell death under hypoxia. Therefore, CA IX has become a reliable histochemical marker of hypoxia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Carbonic Anhydrase IX
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone 053
Concentration 0.1 mg/mL
Conjugate FITC
Formulation PBS with 0.5% BSA and 0.03% ProClin 300
Gene CA9
Gene Accession No. Q16790
Gene Alias Ca9; CA-9; CAIX; CA-IX; Car9; Carbonate dehydratase IX; carbonic anhydrase 9; Carbonic anhydrase IX; carbonic dehydratase; G250; Membrane antigen MN; membrane antigen MN homolog; MN; MN/CA9; P54 / 58N; P54/58N; pMW1; RCC-associated antigen G250; RCC-associated protein G250; renal cell carcinoma-associated antigen G250
Gene Symbols CA9
Host Species Rabbit
Immunogen Recombinant Human Carbonic Anhydrase IX/CA9 Protein.
Purification Method Protein A
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 768
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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