Invitrogen™ Carboxypeptidase A1 Monoclonal Antibody (03)

Catalog No.	Quantity
PIMA529176	100 μL

Catalog No. PIMA529176 Supplier Invitrogen™ Supplier No. MA529176

Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Carboxypeptidase A1/CPA1.

CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.

Specifications

• Antigen: Carboxypeptidase A1
• Applications: Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: 03
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: Cpa1
• Gene Accession No.: P15085
• Gene Alias: 0910001L12Rik; carboxypeptidase A; carboxypeptidase A1; carboxypeptidase A1 (pancreatic); carboxypeptidase A1, pancreatic; CPA; Cpa1; pancreatic carboxypeptidase A; pancreatic procarboxypeptidase A
• Gene Symbols: Cpa1
• Host Species: Mouse
• Immunogen: Recombinant Human Carboxypeptidase A1/CPA1 Protein (Met1-Tyr419).
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1357
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1