Invitrogen™ Carboxypeptidase A1 Monoclonal Antibody (CL6607)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531440

Catalog No. PIMA531440

Description

Immunogen sequence: DFVGHQVLRI SVADEAQVQK VKELEDLEHL QLDFWRGPAH PGSPIDVRVP FPSIQAVKIF LESHGISYET.

CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.

Specifications

• Antigen: Carboxypeptidase A1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P15085
• Gene Symbols: Cpa1
• Immunogen: Recombinant protein corresponding to Human CPA1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: CL6607
• Conjugate: Unconjugated
• Gene: Cpa1
• Gene Alias: 0910001L12Rik; carboxypeptidase A; carboxypeptidase A1; carboxypeptidase A1 (pancreatic); carboxypeptidase A1, pancreatic; CPA; Cpa1; pancreatic carboxypeptidase A; pancreatic procarboxypeptidase A
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1357
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid