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Invitrogen™ Carboxypeptidase A1 Polyclonal Antibody
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Catalog No. PIPA5114942
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100 μL
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PIPA5114942 100 μL
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Catalog No. PIPA5114942 Supplier Invitrogen™ Supplier No. PA5114942
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Carboxypeptidase A.

CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Carboxypeptidase A1
Applications Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene Cpa1
Gene Accession No. P15085, Q7TPZ8
Gene Alias 0910001L12Rik; carboxypeptidase A; carboxypeptidase A1; carboxypeptidase A1 (pancreatic); carboxypeptidase A1, pancreatic; CPA; Cpa1; pancreatic carboxypeptidase A; pancreatic procarboxypeptidase A
Gene Symbols Cpa1
Host Species Rabbit
Immunogen A synthesized peptide derived from human CPA1(Accession P15085), corresponding to amino acid residues A301-G351.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109697, 1357
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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