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Carboxypeptidase B2 Monoclonal Antibody (19E2), Invitrogen™

Catalog No. PIMA125769
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200 μg
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PIMA125769 200 μg
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Catalog No. PIMA125769 Supplier Thermo Scientific Supplier No. MA125769

Mouse Monoclonal Antibody

MA1-25769 detects Carboxypeptidase B2 from human samples.

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Carboxypeptidase B2
Applications Affinity Purification, ELISA, Western Blot
Classification Monoclonal
Clone 19E2
Concentration 4 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene CPB2
Gene Accession No. Q96IY4
Gene Alias 1110032P04Rik; 4930405E17Rik; AI255929; carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase B-like protein; carboxypeptidase R; Carboxypeptidase U; Cpb2; CPR; CPU; pCPB; Plasma carboxypeptidase B; Tafi; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
Gene Symbols CPB2
Host Species Mouse
Immunogen Purified, full length, native human protein.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1361
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1
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