Invitrogen™ Carboxypeptidase B2 Monoclonal Antibody (5026)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA143024

Catalog No. PIMA143024

Description

MA1-43024 detects TAFI in human samples. MA1-43024 has successfully been used in WB, ELISA, IA applications. MA1-43024 was derived from human TAFI and activated TAFI.

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.

Specifications

• Antigen: Carboxypeptidase B2
• Classification: Monoclonal
• Concentration: 10.2 mg/mL
• Formulation: 50% water with 50% glycerol and no preservative
• Gene Accession No.: Q96IY4
• Gene Symbols: CPB2
• Immunogen: Human TAFI.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Inhibition Assays, Western Blot
• Clone: 5026
• Conjugate: Unconjugated
• Gene: CPB2
• Gene Alias: 1110032P04Rik; 4930405E17Rik; AI255929; carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase B-like protein; carboxypeptidase R; Carboxypeptidase U; Cpb2; CPR; CPU; pCPB; Plasma carboxypeptidase B; Tafi; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
• Host Species: Mouse
• Purification Method: SDS-PAGE
• Regulatory Status: RUO
• Gene ID (Entrez): 1361
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov