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Invitrogen™ Carboxypeptidase B2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579063

Catalog No. PIPA579063


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Description

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human placenta tissue, HEPG2 whole cell. IHC: human lung cancer tissue.

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Carboxypeptidase B2
Polyclonal
Unconjugated
CPB2
1110032P04Rik; 4930405E17Rik; AI255929; carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase B-like protein; carboxypeptidase R; Carboxypeptidase U; Cpb2; CPR; CPU; pCPB; Plasma carboxypeptidase B; Tafi; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
Rabbit
Antigen Affinity Chromatography
RUO
1361
-20°C
Lyophilized
ELISA, Immunohistochemistry (Paraffin), Western Blot
500 μg/mL
PBS with 5mg BSA and 0.05mg sodium azide
Q96IY4
CPB2
E. coli-derived human CPB2 recombinant protein (Position: K166-D388).
100 μg
Primary
Human
Antibody
IgG
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