Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. FEMA550464

Invitrogen™ CARD10 Recombinant Rabbit Monoclonal Antibody (HL2261)
GREENER_CHOICE

Catalog No. FEMA550464
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
FEMA550464 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. FEMA550464 Supplier Invitrogen™ Supplier No. MA550464
Add to Cart
Add to Cart

Description

Rabbit Recombinant Monoclonal Antibody

CARD10 Recombinant Monoclonal Antibody for Western Blot

CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. As with CARMA1, the CARD domain of CARMA3 has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-Kappa-B activation. When expressed in cells, this protein binds to BCL10 and activates NF-Kappa-B Recent experiments have shown that CARMA3 is required for EGF-induced NF-Kappa-B activation and contributes to tumor growth in vivo, suggesting that CARMA3 may serve as a new therapeutic target for the treatment of EGFR-driven tumors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CARD10
Applications Western Blot
Classification Recombinant Monoclonal
Clone HL2261
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CARD10
Gene Accession No. P58660, Q9BWT7
Gene Alias AI449026; Bcl10 binding protein and activator of NFKB; bcl10-interacting MAGUK protein 1; Bimp1; Card10; CARD-containing MAGUK 3 protein; CARD-containing MAGUK protein 3; Carma 3; Carma3; caspase recruitment domain family member 10; caspase recruitment domain family, member 10; caspase recruitment domain-containing protein 10
Gene Symbols CARD10
Host Species Rabbit
Immunogen Recombinant fragment of human CARD10.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 105844, 29775, 315120
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.