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CARD4 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987716
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50-198-7716 100 μL
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Catalog No. 50-198-7716 Supplier Bioss Supplier No. BS7085R
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Description

Rabbit Polyclonal Antibody

NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-kappa-B. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

Specifications

Antigen CARD4
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NOD1
Gene Accession No. Q9Y239
Gene Alias C230079P11; CARD4; caspase recruitment domain 4; caspase recruitment domain family, member 4; Caspase recruitment domain-containing protein 4; CLR7.1; F830007N14Rik; NLR family, CARD domain containing 1; Nlrc1; Nod1; nucleotide binding oligomerization domain containing 1; nucleotide-binding oligomerization domain containing 1; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1; Nucleotide-binding oligomerization domain-containing protein 1; RGD1562269
Gene Symbols NOD1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CARD4.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10392
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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