Invitrogen™ CARD9 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529189

Catalog No. PIPA529189

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, NIH-3T3. Predicted reactivity: Mouse (91%), Rat (94%), Bovine (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.

Specifications

• Antigen: CARD9
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CARD9
• Gene Alias: CANDF2; card 9; Card9; caspase recruitment domain family member 9; caspase recruitment domain family, member 9; caspase recruitment domain protein 9; caspase recruitment domain-containing protein 9; Gm782; hCARD9; rCARD9; RP11-413M3.9
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 332579, 64170
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: A2AIV8, Q9H257
• Gene Symbols: CARD9
• Immunogen: Recombinant fragment corresponding to a region within amino acids 36 and 249 of Human CARD9.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG