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Invitrogen™ Cardiac Troponin C Polyclonal Antibody
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Catalog No. PIPA5119941
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100 μL
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PIPA5119941 100 μL
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Catalog No. PIPA5119941 Supplier Invitrogen™ Supplier No. PA5119941
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Description

Rabbit Polyclonal Antibody

Positive Control: Human heart tissue lysates, MG-63, SKOV-3, SW620, rat skeletal muscle tissue, rat heart tissue, mouse heart tissue. Subcellular Location: Cardiac Troponin complex, troponin complex, cytosol.

Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cardiac Troponin C
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Tnnc1
Gene Accession No. P19123, P63316
Gene Alias AI874626; cardiac 3; cardiac troponin C; Cardiac troponin I; CMD1FF; CMD1Z; CMD2A; CMH13; CMH7; cTnC; cTnI; MGC116817; RCM1; slow twitch skeletal/cardiac muscle troponin C; Tn1; TnC; TN-C; Tncc; Tni; TNN I3; TNNC; TNNC 1; Tnnc1; TNNI3; troponin C type 1 (slow); troponin C, cardiac/slow skeletal; troponin C, slow skeletal and cardiac muscles; troponin C1, slow; troponin C1, slow skeletal and cardiac type; Troponin I; Troponin I cardiac; TroponinI
Gene Symbols Tnnc1
Host Species Rabbit
Immunogen Recombinant full length protein of human TNNC1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21924, 290561, 7134
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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