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Invitrogen™ Cardiac Troponin C Recombinant Rabbit Monoclonal Antibody (8Z4V9)
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Catalog No. PIMA542838
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100 μL
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PIMA542838 100 μL
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Catalog No. PIMA542838 Supplier Invitrogen™ Supplier No. MA542838
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: Mouse heart, Rat heart . Immunogen sequence: MDDIYKAAVE QLTEEQKNEF KAAFDIFVLG AEDGCISTKE LGKVMRMLGQ NPTPEELQEM IDEVDEDGSG TVDFDEFLVM MVRCMKDDSK GKSEEELSDL.

Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cardiac Troponin C
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 8Z4V9
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Tnnc1
Gene Accession No. P19123
Gene Alias AI874626; cardiac 3; cardiac troponin C; Cardiac troponin I; CMD1FF; CMD1Z; CMD2A; CMH13; CMH7; cTnC; cTnI; MGC116817; RCM1; slow twitch skeletal/cardiac muscle troponin C; Tn1; TnC; TN-C; Tncc; Tni; TNN I3; TNNC; TNNC 1; Tnnc1; TNNI3; troponin C type 1 (slow); troponin C, cardiac/slow skeletal; troponin C, slow skeletal and cardiac muscles; troponin C1, slow; troponin C1, slow skeletal and cardiac type; Troponin I; Troponin I cardiac; TroponinI
Gene Symbols Tnnc1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNNC1 (P63316).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21924, 290561
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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